Summary: Terazosin, a medication commonly used for enlarged prostate and high blood pressure, shows potential as a treatment for motor neuron disease (MND), also known as amyotrophic lateral sclerosis (ALS). Source: University of Edinburgh A drug already prescribed for benign prostatic hyperplasia and hypertension has demonstrated protective effects on motor neurons in laboratory and animal … Read more

Brain Structure Predicts Whether People Represent Numbers Spatially or Non‑Spatially A new study from the Donders Institute in Nijmegen demonstrates that the way individuals mentally represent numbers—either along a spatial line or via non‑spatial magnitudes—has a measurable structural basis in the brain. Many people mentally organize numbers along an imaginary horizontal line, with smaller numbers … Read more

Study implicates new gene in multiple sclerosis disease activity A study led by researchers at Brigham and Women’s Hospital (BWH) identifies a genetic variant linked to altered response to interferon‑beta, a commonly used treatment for multiple sclerosis (MS). Published in Annals of Neurology on May 14, the report highlights SLC9A9 as a candidate gene that … Read more

The Ancient Art of Ikebana Inspires Bioprinting of Brain Organoids for Personalized Cancer Research Summary: Researchers adapted principles from the traditional Japanese art of flower arranging to develop a bioprinting method that creates miniature brain organoids, offering a more realistic platform for studying glioblastoma and testing personalized treatment strategies. Source: University of British Columbia From … Read more

Summary: A new Swedish twin study shows that how long an infant cries is strongly influenced by genetics, with heritability estimates rising from roughly 50% at two months to about 70% by five months. The study also finds that night awakenings and how quickly infants settle are more affected by environmental factors such as sleep … Read more

Summary: Individuals who score higher on dark personality traits are more likely to accept fake news, particularly when the false information aligns with their self-interest. Even when confronted with scientific evidence, people with these traits tend to reshape facts to suit their preferences. The study found that stronger self-interested tendencies made it harder for participants … Read more

Summary: Researchers have produced a new map that reveals how proteins associate across brain networks. The map is integrated into a software platform that lets scientists visualize where disease-related risk factors operate within those networks. Source: USC. A new study of protein interactions provides a foundation for developing treatments that target dysfunctional pathways in the … Read more

Summary: New research highlights the habenula, a small but influential brain region, as a central regulator of reward, motivation, and emotional states. Studies show habenula circuits shape how the brain responds to reward and disappointment and how it develops drug cravings. This work has revealed promising drug targets—most notably the GPR151 receptor—that could help reduce … Read more

Summary: A new study reveals that, under stress, the brain produces its own cannabinoid molecules—chemicals that act on the same receptors as THC from cannabis—to help reduce stress signals and promote adaptive responses. These endocannabinoids are produced in the amygdala and act to suppress stress-related input coming from the ventral hippocampus, a brain region involved … Read more

Summary: Researchers describe a newly discovered cellular mechanism that can reverse the accumulation of protein aggregates by refolding them rather than degrading them. Source: University of Cambridge Small amounts of stress can sometimes be beneficial. New research shows that, in cells, a specific stress response may help undo harmful protein tangles linked to dementia by … Read more