New Regulator Halts Protein Aggregates in Huntington’s Disease

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Huntington’s disease (HD) is a progressive neurodegenerative disorder marked by the accumulation of abnormal huntingtin protein aggregates in the brain. A new study published in Genome Research introduces a computational approach that pinpoints huntingtin interaction partners and identifies CRMP1 as a previously unrecognized factor that reduces huntingtin misfolding and aggregation. Huntington’s disease arises when the … Read more

Balance Training Improves Mobility in Multiple Sclerosis

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Summary: A controlled trial published in Neurology suggests that a targeted program of balance and eye-movement exercises can reduce balance impairment and fatigue in people with multiple sclerosis (MS). Source: AAN. A structured rehabilitation program combining balance training with eye movement exercises improved balance and reduced fatigue in people with multiple sclerosis (MS), according to … Read more

How Brain Structure Changes Affect Cognition

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Summary: A neuroimaging study links age-related decline in specific white matter circuits to reduced efficiency of executive function in older adults. Source: UT Dallas As people age, the brain’s communication pathways gradually degrade, and this decline in circuit integrity can undermine cognitive performance even in otherwise healthy adults. Researchers at The University of Texas at … Read more

Why We Cannot Recognize Our Own Conspiracy Beliefs

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Summary: A recent study from the University of Illinois Chicago indicates that many people struggle to recognize their own beliefs as conspiracy theories, a phenomenon the researchers call “conspiracy blindness.” Although sizable portions of the public endorse ideas that meet the criteria for conspiratorial thinking, participants in the study often failed to label those ideas … Read more

Brown Fat Improves Blood Sugar Control

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Australian researchers report that brown fat — a unique form of fat that burns calories to produce heat — may also help stabilise blood sugar levels in adults. Scientists at the Garvan Institute of Medical Research in Sydney monitored brown fat activity and blood glucose continuously in real time and found that people with more … Read more

Microbiome Antibiotic Disrupts Bacterial Energy Metabolism

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Summary: A synthetic version of a peptide produced by human-associated bacteria shows promise against antibiotic-resistant pathogens. The molecule, derived from a naturally occurring compound called lugdunin, disrupts bacterial energy processes and is active against MRSA. These results point toward a new class of antibiotics that could treat infections resistant to current drugs. Source: German Center … Read more

How the Brain Stores Memories: New Study Reveals Filing System

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Summary: A new NYU study shows that, over time, the brain organizes individual experiences by their shared features, forming clusters that may support conceptual knowledge. Source: NYU Neuroscientists at New York University report that our brains reorganize experiences across time, grouping memories by similarity. Researchers led by Lila Davachi, associate professor in NYU’s Department of … Read more

War’s Impact on Ukrainians: Rising PTSD and Anxiety

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Summary: A new study reports widespread and severe mental health effects among displaced Ukrainians following Russia’s full-scale invasion. Surveying more than 8,300 people who were either refugees or internally displaced within Ukraine, researchers found high rates of generalized anxiety, post-traumatic stress disorder (PTSD) symptoms including flashbacks and nightmares, and a clear link between exposure to … Read more

How Impulse Control Disorders Alter Risky Decision-Making

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Summary: A new study examines how people with Parkinson’s disease — especially those who develop impulse control disorders (ICD) after taking dopaminergic medications — evaluate and emotionally respond to the outcomes of risky decisions. In a controlled experiment with 30 participants, researchers compared decision-making and emotional reactions between patients with ICD and those without, tested … Read more

Mediterranean Diet Boosts Memory and Cognitive Function

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Summary: A study finds a clear association between following the Mediterranean diet and better cognitive function. Source: RUVID The Mediterranean diet is well known for supporting cardiovascular health, but new evidence shows it can also improve memory and help prevent or delay age-related cognitive decline. These cognitive benefits are not uniform across all people, highlighting … Read more