Serotonin Drives Social Aversion in Opioid Withdrawal
Summary: In mice, opioid withdrawal disrupts serotonin signaling to the nucleus accumbens, causing pronounced reductions in sociability and increased social avoidance. Source: Stanford Opioid withdrawal is not only physically painful but also sharply reduces social motivation, a change that undermines recovery by driving isolation at precisely the time when social support is most needed. “Self-isolation … Read more