Single-Molecule Latch Redefines Taste Perception
Summary: Scientists have resolved the first three-dimensional crystal structure of an umami taste receptor ortholog from pufferfish, revealing a distinctive molecular latch…
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Scientists Identify Brain Circuit Driving Pregnancy Food Cravings
Summary: Researchers have identified a specific neural circuit and molecular mechanism that explain the strong food cravings many people experience during pregnancy.…
Disrupted Striatal D2 Receptors Drive ADHD and Impulsivity
Summary: Researchers at the University of Fukui found that deleting the membrane-fusion protein NSF (N-ethylmaleimide-sensitive factor) specifically from dopamine D2 receptor (D2R)-expressing…
Why the Brain Acts Like Two Organs Joined by Evolution
Summary: Challenging long-held assumptions about brain development, researchers have shown that the vertebrate brain does not arise from a single ancestral progenitor.…
Blue Brain Region Reveals How Norepinephrine Drives Learning
Summary: Researchers at the Allen Institute have overturned a long-standing idea about how the brainstem nucleus called the locus coeruleus (LC) operates.…
Lab-Grown Human Brain Tissue Restores Neural Circuits in Mice
Summary: Neuroscientists have created a genetic approach that produces mice missing the majority of their cerebral cortex, opening a large physical niche…
Common Molecular Signatures of Autism Genes in the Brain
Summary: A large-scale analysis of over 1,000 mouse prefrontal cortex transcriptomes across 17 genetically engineered lines reveals that more than 1,200 autism…
Key Genetic Switch Directs Long-Range Axon Guidance
Summary: Neuroscientists have overturned the long-standing idea that growing axons make all navigational decisions only at their tips. New research shows that…
Disadvantaged Neighborhoods Linked to Faster Brain Aging
Summary: A large clinical MRI study of 2,826 patients shows that living in socioeconomically disadvantaged neighborhoods is linked to measurable signs of…
Brain Signals Predict Risky Choices 0.5 Seconds Before Decision
Summary: Using direct recordings from electrodes implanted in the human orbitofrontal cortex, researchers have identified two neighboring neural circuits that engage in…
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