Summary: Researchers found that eye contact acts as an intentional switch that synchronizes brainwaves between infants and adult speakers, directly supporting selective language learning. A cross-cultural study recorded brain activity in 8- to 10-month-old infants with electroencephalography (EEG) while they listened to novel, nonsense languages. The research team discovered that infants learned a new language … Read more

Summary: Researchers have developed an energy-efficient artificial intelligence model inspired by hippocampal mechanisms in the brain. The system reproduces how the human brain builds cognitive maps, performs stochastic computations, and uses compositional codes to solve complex planning tasks without exhaustive calculation. Presented as a proof-of-concept for alternative AI architectures, the model adapts flexibly to unfamiliar … Read more

Summary: Researchers have developed Core2Edge, an advanced human ex vivo tissue model that reproduces the invasive spread and molecular heterogeneity of glioblastoma. By combining patient-derived glioblastoma organoids with organotypic human brain-slice cultures, this platform enables high-resolution spatial tracking of infiltrating tumor cells as they move into healthy brain tissue. Core2Edge integrates expanded light-sheet fluorescence microscopy … Read more

Summary: New research shows that keeping a consistent daily routine can lower physical pain and ease depressive symptoms, offering a straightforward approach to improve quality of life—especially for older adults who experience insomnia. Researchers examined survey data from older adults with and without insomnia to determine how regular behavioral and social rhythms affect health. The … Read more

Summary: A landmark randomized controlled trial carried out in low-resource neighborhoods of South Delhi, India, shows that a structured, home-based integrated intervention substantially improves growth, reduces anemia, enhances neurodevelopment, and lowers mortality among term small-for-gestational-age (SGA) infants. This trial enrolled 1,300 term SGA infants within 14 days of birth and followed them to 12 months … Read more

Summary: Topline results from the Phase 2 LiBBY clinical trial show that a targeted oral oil formulation combining cannabidiol (CBD) and tetrahydrocannabinol (THC) produced rapid and sustained reductions in severe agitation in hospice-eligible people with advanced dementia. The multicenter, randomized, double-blind, placebo-controlled trial evaluated a novel digestible oil formulation (designated T2) in 120 hospice-eligible dementia … Read more

Summary: Researchers have shown that a targeted antioxidant therapy can overcome the neurodevelopmental deficits associated with 22q11.2 deletion syndrome by engaging alternative cellular pathways, without repairing the underlying chromosomal deletion. Using a validated mouse model of 22q11.2 deletion syndrome — the second most common chromosomal microdeletion in humans and a major genetic risk factor for … Read more

Summary: Intracranial recordings in humans reveal that sleep-dependent memory consolidation requires tightly coordinated activity among three brain regions—the orbitofrontal cortex, the thalamus, and the hippocampus. This coordinated cascade of slow oscillations, sleep spindles, and hippocampal ripples strengthens memory traces, while interictal epileptic spikes disrupt that timing and impair memory. Researchers used simultaneous intracranial recordings to … Read more

Summary: Engineers and neuroscientists have created a soft, battery-free fingertip patch that continuously measures levodopa levels in human sweat in real time, providing a noninvasive, wearable way to monitor Parkinson’s medication levels with lab-comparable accuracy. This wearable uses an engineered absorbent salt gel to harvest sweat from the fingertip’s dense network of sweat glands. Enzymes … Read more

Summary: A commentary argues that the United States is likely undercounting suicide deaths because many fatal drug overdoses are being classified as accidental or of undetermined intent. The authors recommend adopting a public‑health surveillance approach called Self‑Injury Mortality (SIM) that groups registered suicides with drug self‑intoxication deaths to better capture self‑directed fatal behaviors. Researchers note … Read more