New Platform Accelerates VR Cybersickness Research and Testing

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Summary: A novel, large-scale remote study has launched to investigate cybersickness — a common barrier to virtual reality (VR) adoption. Cybersickness arises from a sensory-motor conflict: the headset’s convincing visual motion signals movement while the user’s body remains physically still, producing symptoms such as nausea, dizziness, and discomfort. To scale beyond the limitations of traditional … Read more

Personalized fMRI Guides TMS to Better Depression Outcomes

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Summary: A randomized clinical trial indicates that using individualized brain imaging to guide transcranial magnetic stimulation (TMS) significantly improves outcomes for people with treatment-resistant depression. Investigators found that selecting stimulation targets from each person’s resting-state functional magnetic resonance imaging (fMRI) connectivity map produced larger antidepressant effects than standard scalp-based targeting. The study used accelerated TMS … Read more

How Dogs Could Accelerate Autism Drug Discovery

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Summary: For three decades, the development of effective pharmacological treatments for autism spectrum disorder (ASD) has repeatedly stalled: more than 90% of candidate drugs that succeed in preclinical models fail in human clinical trials. A new peer-reviewed Perspective proposes an unexpected solution: leveraging the laboratory Beagle as a translational model that better captures the social … Read more

GABA Immune Signaling Promotes Brain Tumor Growth in Women

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Summary: Glioblastoma, the most common and deadly brain cancer, shows clear differences between men and women in how often it occurs, how it responds to treatment, and survival. New research has uncovered a sex-specific biological mechanism: the neurotransmitter GABA (gamma-aminobutyric acid) selectively reprograms a subset of immune cells in females, creating an immunosuppressive environment that … Read more

Daylight Exposure Linked to Lower Dementia Risk

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Summary: A large prospective study has identified a clear association between everyday environmental light and long-term cognitive health. Researchers found that people who receive higher levels of daytime light have a substantially lower risk of developing dementia over time. In this study, daytime and nighttime light exposure were measured in 87,577 adults using wrist-worn accelerometers … Read more

How Single Neurons Control Language Switching in Bilingual Brains

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Summary: For people who speak two languages, switching between them often feels effortless. A new study now explains how the brain achieves that seamless transition at the level of single neurons. The research finds that bilingual brains encode meaning in a shared semantic map that spans languages, while individual hippocampal neurons remain largely language-specific and … Read more

Heart Rate Synchrony in Real-World Social Interactions

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Summary: When people share space and attention, their bodies often fall into the same rhythm. A new naturalistic study shows that when individuals are close—physically and emotionally—their heart rates tend to align, rising and falling together. This physiological synchrony appears reliably in everyday settings and may be used as an objective marker of social engagement. … Read more

Personalized fMRI-Guided TMS Improves Depression Outcomes

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Summary: A randomized clinical trial from Mass General Brigham indicates that using each patient’s resting-state functional MRI (fMRI) to select targets for transcranial magnetic stimulation (TMS) can meaningfully improve outcomes for treatment-resistant major depressive disorder. The study found that connectivity-based targeting — selecting stimulation sites based on individualized functional connectivity maps — produced larger antidepressant … Read more

How Human Memory Limits Help AI Excel at Grammar

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Summary: Contemporary AI language models often rely on very large, unconstrained context windows to process text, retaining extensive contextual information across long stretches of text. That brute-force approach scales well for very large systems, but it does not mirror how young children learn language: humans extract structure from far more limited, rapidly decaying memory traces. … Read more

First Embryonic Stem Cell Trial for Huntington’s Disease Begins

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Summary: Huntington’s disease is a progressive, ultimately fatal genetic disorder that destroys nerve cells in the brain, stripping people of motor control, cognitive abilities, and emotional stability. Symptoms typically appear in adulthood (most often between ages 35 and 50) and worsen steadily over a decade or more, placing a heavy emotional and financial burden on … Read more