Summary: Researchers report that fruit flies (Drosophila melanogaster) find odor sources not by simple reflexes but by using a directional memory system. This internal vector-based strategy lets them track the edge of an odor plume and reorient back to the scent even when the plume shifts or the wind changes. Using a virtual-reality treadmill combined … Read more

Summary: Researchers have introduced the world’s first chip engineered to operate at the millisecond timescale of the human brain. Built on a standard 40-nanometer manufacturing process, this sub-10-millisecond neural dynamical system uses phase-change memristors to perform core mathematical operations directly inside memory. The complete design fits within 0.28 square millimeters and delivers dramatic performance and … Read more

Summary: A comprehensive analysis of immune cells from human blood, cerebrospinal fluid (CSF), and intestinal mucosal tissue in control individuals and multiple sclerosis (MS) patients treated with B-cell depletion reveals a previously unrecognized mechanism. Rather than working solely by removing disease-driving B cells, anti-B-cell therapy appears to alter systemic regulatory signals and actively mobilize protective, … Read more

Summary: Using high-speed videography and automated pose estimation, researchers found that individual hummingbird hawkmoths consistently place the tip of their proboscis to one side of their body midline while inspecting flowers. This motor bias aligns with a dominant eye, forming a stable eye–proboscis–target control axis that reduces computational demands on the moth’s small brain. Key … Read more

Summary: In a 6-hydroxydopamine (6-OHDA) mouse model of Parkinson’s disease, researchers gave daily doses of L‑DOPA/carbidopa from day 13 to day 30 after lesion, either alone or combined with freeze-dried bee venom. Behavioral testing showed that the combination produced markedly better outcomes than standard therapy alone. Mice treated with L‑DOPA/carbidopa plus bee venom preserved nearly … Read more

Summary: Researchers have identified a previously unrecognized exit route for cerebrospinal fluid (CSF): tiny openings in the arachnoid membrane, termed arachnoid fenestrations. These 2–12 micrometer pores are concentrated in a specialized lymphatic zone between the olfactory bulbs and the cribriform plate. CSF flows through these fenestrations into meningeal lymphatic vessels, passes through the nasal mucosa, … Read more

Summary: Researchers at the University of Virginia have developed a non‑invasive method to deliver therapeutic microRNAs across the blood‑brain barrier (BBB). Using MRI‑guided focused ultrasound (FUS) together with circulating microbubbles, they transiently open tight endothelial junctions in specific brain regions so brain‑penetrating nanoparticles carrying miRNAs can enter the tumor microenvironment. In preclinical glioblastoma models, this … Read more

Summary: A systematic review of clinical trials finds that structured, organized sports programs can meaningfully improve motor skills in children with Autism Spectrum Disorder (ASD). Across 11 studies, martial arts (notably Tai Chi Chuan and kata) and aquatic training produced the most consistent and largest improvements in balance, overall motor performance, and object control. Other … Read more

Summary: Researchers report the first direct electrophysiological evidence that caffeine alters taste perception at the organoid level. They created a biomimetic taste sensor by combining three-dimensional taste bud organoids with a custom 3D microelectrode array (3D MEA) whose vertical electrodes extend roughly 200 micrometers into the tissue. This spatially penetrating design records volumetric bioelectrical activity … Read more

Summary: A research team has developed a high-resolution adaptive light-sheet microscopy system that enables rapid, real-time 3D imaging of brain-wide seizure dynamics. By integrating an electrically tunable lens for ultra-fast axial scanning with synchronized, millisecond-scale sensorless adaptive optics, the microscope corrects optical aberrations on the fly while preserving image speed and near-diffraction-limited resolution. Key Facts … Read more