Summary: Researchers have discovered a new gene linked to a form of syndromic autism and uncovered how its mutation can contribute to the condition. Source: Institute of Science and Technology Austria An international research team led by IST Austria scientists has identified a new genetic cause of syndromic autism; the study was published in Cell. … Read more

Summary: New research reports increased levels of Alzheimer’s-related tau protein in children and adolescents with early onset psychosis. Source: IEPA Higher Levels of Alzheimer’s-Related Tau Found in Young People With Early Onset Psychosis New findings presented at the International Early Psychosis Association (IEPA) meeting in Milan, Italy (October 20–22) indicate that a specific form of … Read more

Summary: An international study finds that speakers slow down before saying nouns more often than before verbs, suggesting nouns require more planning because they typically introduce new information. Source: Leiden University Why do we sometimes speak more slowly or more quickly, and why do pauses vary between words? Researchers led by linguist Frank Seifart (University … Read more

Summary: Researchers report that people who experience social exclusion are more likely to accept disinformation, fake news and conspiracy theories. Source: Princeton University. Recent polls indicate that many white, working-class Americans feel marginalized—a sentiment that helped drive support for President Donald Trump. For some, that sense of exclusion made them more receptive to misleading information … Read more

Summary: New research indicates Parkinson’s disease can develop silently for more than a decade before motor symptoms appear. The study shows that neural circuits controlling movement remain functional even after a dramatic reduction in activity-dependent dopamine release—challenging common assumptions about the immediate role of dopamine loss in producing motor deficits. Dopamine is widely recognized as … Read more

Summary: Patients diagnosed with Borderline Personality Disorder (BPD) are more likely to have repeated hospital visits than people with other mental health diagnoses. In a review of 86,740 emergency department and inpatient episodes involving 25,619 mental health patients across South Australian public hospitals from 2014 to 2019, researchers found that BPD has a measurable impact … Read more

Summary: For years, brain swelling has been the most feared complication of the newest anti-amyloid Alzheimer’s therapies, including lecanemab and donanemab. This swelling, known as ARIA-E (amyloid-related imaging abnormality with edema), commonly prompts clinicians to slow or pause treatment. A new study from Houston Methodist Research Institute suggests a different perspective: ARIA-E may mark regions … Read more

Summary: Reduced blood flow to specific brain regions parallels accumulation of tau protein in people with Alzheimer’s disease. This link grows stronger as cognitive function declines, suggesting vascular dysfunction and tau pathology interact during disease progression. Source: SfN New research published in Journal of Neuroscience finds that impaired blood flow in targeted brain regions coincides … Read more

Summary: Time-restricted eating alters gene expression across more than twenty-two regions of the brain and body in mice, revealing coordinated molecular changes that may underlie the wide-ranging health benefits linked to this dietary pattern. Source: Salk Institute Time-restricted eating and related practices such as intermittent fasting have been associated with multiple health benefits in animal … Read more

Summary: A large genetic study has identified 956 genes linked to an increased risk of insomnia and mapped the brain regions, cell types, and biological pathways that mediate that genetic risk. Source: VRIJE University Amsterdam. An international research consortium has, for the first time, pinpointed the specific brain cell types, regions and biological processes that … Read more