How Ketamine Alters Brain Activity
Summary: A new computational model clarifies how ketamine, an anesthetic and rapid-acting antidepressant, changes brain activity. By simulating ketamine’s interactions with NMDA receptors in cortical circuits, the model links molecular blocking to altered neuronal firing patterns and the oscillatory brain states associated with dissociation, sedation, and potential therapeutic benefits for depression. Key Facts: Ketamine acts … Read more