Summary: A new Columbia University analysis shows depression burden in the United States is highest among women, adolescents and young adults, while treatment levels remain low. Source: Columbia University A recent study by researchers at Columbia University Mailman School of Public Health and the City University of New York reports widespread increases in depression across … Read more

Summary: New research from the University of Eastern Finland indicates that a prior traumatic brain injury (TBI) raises the likelihood of developing frontotemporal dementia (FTD) among people without a known genetic cause. The studies also find that, on average, people with FTD have lower educational attainment than those with Alzheimer’s disease, and that some cardiovascular … Read more

A company’s success depends on effective individuals and well-integrated teams. Collaborating productively, maintaining high performance, and supporting employee wellbeing are essential for sustained business results. Interpersonal dynamics are shaped largely by personality rather than only by technical skills or expertise. Consequently, many organizations use personality profiling to assemble balanced, high-performing teams. This article reviews one … Read more

Glymphatic System: How the Brain Clears Waste and Why It Matters for Alzheimer’s Researchers at the University of Rochester Medical Center describe a recently characterized brain waste-clearance pathway—the glymphatic system—as a promising target for treating neurological disorders such as Alzheimer’s disease. They suggest that impaired clearance of cellular waste may contribute to the development of … Read more

Tanning Activates Addictive Pathways in the Brain Researchers at the University of Colorado Anschutz Medical Campus have identified a clear association between indoor tanning and substance use among Colorado high school students. Their analysis, published in JAMA Dermatology, suggests that motivations for indoor tanning and overlapping biological mechanisms may help explain why tanning is linked … Read more

You’re unlikely to meet anyone who enjoys interviews. No matter your experience, interviews often trigger anxiety—usually not because of the interview itself but because of unexpected, personal questions. Beyond basic skills and experience, interviewers may ask questions such as “How good are you at asking for help?” or “How do you create balance in your … Read more

Summary: New research shows that progranulin deficiency may contribute to neurodegeneration in frontotemporal dementia by reducing lysosomal support for key proteases. Source: VIB Flanders Progranulin stabilizes lysosomal enzyme cathepsin D, study finds In a study published in Human Molecular Genetics, researchers at VIB and KU Leuven, led by Professor Philip Van Damme in collaboration with … Read more

Summary: A new study finds that autism-like behaviors appear in mice when two competing neuronal proteins—MDGA2 and BDNF—lose their balance. Under normal conditions, MDGA2 restrains BDNF/TrkB signaling; when MDGA2 levels fall, BDNF/TrkB activity rises, driving increased excitatory neuronal activity and social deficits. Mice with reduced MDGA2 displayed behaviors resembling core features of autism spectrum disorder … Read more

Happiness is such a central idea in life that most people rarely stop to define what it really means or to ask why we devote so much energy to finding it. The pursuit of happiness is more than a philosophical concept; it has long been a cultural ideal. In Western traditions it has been celebrated … Read more

Summary: Researchers have identified how a specific class of neurons helps the brain maintain and focus on short-term information. The team discovered PAC neurons—cells that coordinate the activity of memory-specific neurons through phase-amplitude coupling rather than storing content themselves. These conclusions come from direct brain recordings in epilepsy patients performing memory tests, offering fresh insight … Read more